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Postural Orthostatic Tachycardia Syndrome: A State-of-the-Art Review
Article published in Heart, Lung and Circulation by Dennis Lau, Artur Fedorowski, Satish Raj, Caelum Schild, Laura Pace, Svetlana Blitshteyn, Vidya Raj, Jeffrey Boris, Lesley Kavi, Marie-Claire Seeley, Celine Gallagher Abstract Postural orthostatic tachycardia syndrome (POTS) is a complex disorder mainly of orthostatic intolerance, often accompanied by a spectrum of symptoms related to autonomic nervous system dysfunction. Although the diagnostic criteria require an orthosta
Jan 9
Long‐Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey: Educational, Economic, and Social Impact
Article published in Journal of the American Heart Association by Jeffrey Boris, Edward Shadiack III, Elizabeth McCormick, Laura MacMullen, Ibrahim George‐Sankoh, and Marni J. Falk Abstract Background Limited data exist on long‐term outcomes associated with postural orthostatic tachycardia syndrome (POTS). We designed an online questionnaire to assess outcomes for patients formerly managed in a single‐center pediatric POTS program. Here, we report the educational, economic,
Oct 28, 2025
The Long-Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey-Gynecologic Findings: A Cross-Sectional Survey in Young Women
Article published in Obstetrics and Gynecology International by Jeffrey Boris, Edward Shadiack III, Elizabeth McCormick, Laura MacMullen, Ibrahim George‐Sankoh, Frances Fitzgerald, and Marni J. Falk Abstract Objective : Postural orthostatic tachycardia syndrome (POTS) affects up to 3 million people in the United States. Although 78%–83% of POTS patients are female, gynecologic comorbidity has not been well-studied. We created an online questionnaire to assess outcomes in fem
Jul 15, 2025
Age and sex differences in vasovagal syncope: triggers, clinical presentation, prodromal symptoms, and head-up tilt test results
Article published in European Heart Journal Open by Mohammadreza Babaei, Masih Tajdini, Ali Bozorgi, Saeed Sadeghian, Morvarid Taebi, Hamed Tavolinejad, Mehrdad Mahalleh, Homa Taheri, Florian Rader, Jeffrey Boris, Artur Fedorowski Abstract Aims : Previous studies show inconsistencies in vasovagal syncope (VVS) symptoms and haemodynamic responses across age and sex groups, with limited evaluation of tilt test results. This study comprehensively examines differences in trigger
Jun 11, 2025
Impact of exercise to treat postural orthostatic tachycardia syndrome: a systematic review
Article published in Frontiers in Neurology by Melissa M Cortez, Kayla Aikins, Amy Arnold, Jeffrey Boris, Todd Davenport, Katie Johnson, Hagar Kattaya, Laurence Kinsella, Mary McFarland, Ryan Pelo, Clayton Powers, Kelsi Schiltz, Lauren Stiles, Lauren Ziaks, Tae Hwan Chung, Claudia Dal Molin Abstract Background : Postural orthostatic tachycardia syndrome (POTS) is a chronic condition associated with a high symptom burden and decreased quality of life (QOL). Exercise is curre
Apr 24, 2025
The genetic landscape of pediatric postural orthostatic tachycardia syndrome
Article published in Clinical Autonomic Research by Huiqi Qu, Jingchun Qu, Xiao Chang, Nolan Williams, Frank Mentch, James Snyder, Maria Lemma, Kenny Nguyen, Meckenzie Behr, Michael March, John Connolly, Joseph Glessner, Jeffrey Boris, and Hakon Hakonarson Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a complex disorder with serious health consequences, while its etiology remains largely elusive. Objective The purpose of this study was to investigat
Feb 19, 2025
Comparison of paediatric patients evaluated for postural orthostatic tachycardia syndrome with and without tachycardia
Article published in Cardiology in the Young by Jeffrey Boris, Matthew J. Sniatynski , Thomas Bernadzikowski and Bruce S. Kristal Abstract Introduction: Postural orthostatic tachycardia syndrome is a debilitating disorder. We compared paediatric patients with this dysautonomia presenting with and without peak upright heart rate > 100 beats per minute. Materials and Methods: Subjects were drawn from the Postural Orthostatic Tachycardia Syndrome Program database of the Childre
Sep 13, 2024
Long-Term POTS Outcomes Survey: Diagnosis, Therapy, and Clinical Outcomes
Article published in Journal of the American Heart Association by Jeffrey Boris, Edward Shadiack III, Elizabeth McCormick, Laura MacMullen, Ibrahim George‐Sankoh, and Marni J. Falk Abstract Background Limited data exist on long‐term outcomes in individuals with postural orthostatic tachycardia syndrome (POTS). We designed an electronic questionnaire assessing various aspects of outcomes among patients diagnosed and treated in a single‐center pediatric POTS clinical program.
Jul 3, 2024
Assessment of comorbid symptoms in pediatric autonomic dysfunction
Article published in Clinical Autonomic Research by Jeffrey Boris, Sally E. Tarbell, Erin L. Olufs, Philip R. Fischer, Gisela Chelimsky,...
Sep 20, 2023
How should we measure the “POT” of POTS, and how much does it matter?
Article published in Clinical Autonomic Research by Jeffrey Boris, Philip Fischer Abstract Diagnosis is a system of more or less guessing in which the end-point achievement is a name. These names applied to disease come to assume the importance of specific entities, whereas they are for the most part no more than insecure and therefore temporary conceptions. Sir Thomas Lewis Welsh Cardiologist 1881–1945 Read the full article at PubMed Central®
Sep 1, 2023
Emergency Department utilisation and diagnoses in adolescents with POTS
Article published in Cardiology in the Young by Jeffrey Boris, Thomas Bernadzikowski Abstract Introduction: Data for Emergency Department...
Mar 30, 2023
Creating a data dictionary for pediatric autonomic disorders
Article published in Clinical Autonomic Research by Jeffrey Boris, Hasan Abdallah, Shelley Ahrens, Gisela Chelimsky, Thomas Chelimsky,...
Feb 17, 2023
Pediatric Postural Orthostatic Tachycardia Syndrome: Where We Stand
State of the Art Review article written with Jeffrey Moak, MD, and published in Pediatrics, the journal of the American Academy of...
Jun 24, 2022
Clinical Course of Transgender Adolescents with Complicated POTS Undergoing Hormonal Therapy
Article published in Transgender Health by Jeffrey Boris, Zachary McClain, and Thomas Bernadzikowski Abstract Purpose: Postural...
Jun 23, 2022
Postural orthostatic tachycardia syndrome (POTS): Priorities for POTS care and research
Article published in Autonomic Neuroscience: Basic & Clinical by Satish Raj, Kate Bourne, Lauren Stiles, Mitchell Miglis, Melissa Cortez,...
Oct 31, 2021
Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care
Article published in Autonomic Neuroscience: Basic & Clinical by Steven Vernino, Kate Bourne, Lauren Stiles, Blair Grubb, Artur...
Oct 31, 2021
Prevalence of joint hypermobility syndromes in pediatric postural orthostatic tachycardia syndrome
Article published in Autonomic Neuroscience: Basic & Clinical by Jeffrey Boris, Thomas Bernadzikowski Abstract Introduction: Patients...
Dec 29, 2020
Family history of associated disorders in patients with postural tachycardia syndrome
Article published in Cardiology in the Young by Jeffrey Boris, Jing Huang, Timothy Shuey, Thomas Bernadzikowski Abstract Introduction:...
Feb 3, 2020
Orthostatic heart rate does not predict symptomatic burden in pediatric patients with chronic...
Article published in Clinical Autonomic Research by Jeffrey Boris, Jing Huang, and Thomas Bernadzikowski Abstract Purpose: Postural...
Aug 4, 2019
Therapy for fatigue and cognitive dysfunction in postural orthostatic tachycardia syndrome
Article published in Cardiology in the Young by Jeffrey Boris, Thomas Bernadzikowski IntroductionSevere fatigue and cognitive dysfunction...
Sep 9, 2018
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